December 07, 2014

Depression and Pain Comorbidity

Depression and Pain Comorbidity


Because depression and painful symptoms commonly occur together, a literature review has been conducted in order to determine the prevalence of both conditions and the effects of comorbidity on diagnosis, clinical outcomes, and treatment. A growing body of literature has focused on the interaction between depression and pain symptoms, labeled as the depression-pain syndrome. This review addresses several questions, for example if the presence of depression affects the clinical outcomes in patients treated for pain.



  • Title: Depression and Pain Comorbidity - A Literature Review
  • Authors: Matthew J. Bair, MD, MS; Rebecca L. Robinson, MS; Wayne Katon, MD; Kurt Kroenke, MD
  • Date: November 10, 2003
  • Source: Arch Intern Med. 2003;163(20):2433-2445. doi:10.1001/archinte.163.20.2433, Jama Internal Medicine



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