Depressive & Bipolar Disorders

Depression and Borderline Personality Disorder

We suggest taking a therapeutic stance to MDD co-occurring with BPD that promotes reflection on the patient’s mind and the minds of others.


  • Title: Depression and borderline personality disorder
  • Authors: Josephine A Beatson and Sathya Rao
  • Date: 2012
  • Source: Med J Aust 2013; 199 (6 Suppl): S24-S27. doi:10.5694/mja12.10474

The following link will lead you to the full text article:
Depression and Borderline Personality Disorder



 Depression and Anxiety

Comorbid depression and anxiety are common and affect up to a quarter of patients attending general practice.


  • Title: Depression and anxiety
  • Authors: John W G Tiller
  • Date: 2012
  • Source: Med J Aust 2013; 199 (6 Suppl): S28-S31. doi:10.5694/mja12.10628


The following link will lead you to the full text article:
https://www.mja.com.au/journal/2013/199/6/depression-and-anxiety



Post-stroke depression and the aging brain


The incidence of mental illnesses like anxiety and depression after stroke is estimated at about 35% among the stroke survivals.  Post-stroke depression (PSD) is a frequent neuropsychiatric consequence of cerebral ischemia.  Since stroke and depression are diseases with increased incidence in the elderly, great clinical benefit may come from acquiring knowledge of the basic mechanisms underlying PSD.


  • Title: Review - Post-stroke depression and the aging brain
  • Authors: Gabriel R Cojocaru, Aurel Popa-Wagner, Elena C Stanciulescu, Loredana Babadan and Ana-Maria Buga
  • Date: 2013
  • Source: Journal of Molecular Psychiatry 2013, 1:14  doi:10.1186/2049-9256-1-14   © 2013 Cojocaru et al.; licensee BioMed Central Ltd. 



The following link will lead you to the full text article:
Post-stroke depression and the aging brain




An Instrument for Residual Depression Symptoms 


Most patients with depression continue to experience at least some residual symptoms following treatment. There is an apparent lack of an instrument that easily allows for the discovery, quantification, and tracking of residual symptoms


  • Title: An instrument to guide symptom-specific treatment of residual depression symptoms 
  • Authors: Christopher M. France, Psy.D., Roger Sparhawk, M.D. 
  • Date: 2006
  • Source: Priory Lodge Education Ltd. 



The following link will lead you to the full text article:
An Instrument for Residual Depression Symptoms




Diabetes Mellitus in Bipolar Patients

 The aim of this study was to determine frequency of DM in BMD.

  • Title: DIABETES MELLITUS IN HOSPITALIZED BIPOLAR PATIENTS
  • Authors: Habibolah Khazaie, Soraya Siabani, Mehrali Rahimi, Azita Chehri.
  • Date: N/A
  • Source: Priory Lodge Education Ltd 



The following link will lead you to the full text article:
Diabetes Mellitus in Bipolar Patients




 Anxiety, Depression and Patient Adherence 


This article presents a quantitative review and synthesis of studies correlating treatment noncompliance with anxiety and depression. Compared with nondepressed patients, the odds are 3 times greater that depressed patients will be noncompliant with medical treatment recommendations. The results point to the importance of recognizing depression as a risk factor for poor outcomes among patients who might not be adhering to medical advice.


  • Title: Depression Is a Risk Factor for Noncompliance With Medical Treatment - Meta-analysis of the Effects of Anxiety and Depression on Patient Adherence 
  • Authors: M. Robin DiMatteo, PhD; Heidi S. Lepper, PhD; Thomas W. Croghan, MD
  • Date: 2000
  • Source: Arch Intern Med. 2000;160(14):2101-2107. doi:10.1001/archinte.160.14.2101.



The following link will lead you to the full text article:
Anxiety, Depression and Patient Adherence




 Chocolate and Depressive Symptoms

Much lore but few studies describe a relation of chocolate to mood. This study examined the cross-sectional relationship of chocolate consumption with depressed mood in male and female adults. Higher depression scores were associated with greater chocolate consumption.

  • Title: Mood Food - Chocolate and Depressive Symptoms in a Cross-sectional Analysis 
  • Authors: Natalie Rose, MD; Sabrina Koperski, BS; Beatrice A. Golomb, MD, PhD
  • Date: 2010
  • Source: Arch Intern Med. 2010;170(8):699-703. doi:10.1001/archinternmed.2010.78


The following link will lead you to the full text article:

 Depression and Type 2 Diabetes Mellitus


It has been hypothesized that the diabetes-depression relation is bidirectional. A total of 65 381 women aged 50 to 75 years in 1996 were observed until 2006. This study´s results provide compelling evidence that the diabetes-depression association is bidirectional.



  • Title: Bidirectional Association Between Depression and Type 2 Diabetes Mellitus in Women
  • Authors: An Pan, PhD; Michel Lucas, PhD; Qi Sun, ScD; Rob M. van Dam, PhD; Oscar H. Franco, MD, DSc, PhD; JoAnn E. Manson, MD, DrPH; Walter C. Willett, MD, DrPH; Alberto Ascherio, MD, DrPH; Frank B. Hu, MD, PhD
  • Date: 2010
  • Source: Arch Intern Med. 2010;170(21):1884-1891. doi:10.1001/archinternmed.2010.356.


The following link will lead you to the full text article:
Depression and Type 2 Diabetes Mellitus





 Depression and Pain Comorbidity


Because depression and painful symptoms commonly occur together, a literature review has been conducted in order to determine the prevalence of both conditions and the effects of comorbidity on diagnosis, clinical outcomes, and treatment. A growing body of literature has focused on the interaction between depression and pain symptoms, labeled as the depression-pain syndrome. This review addresses several questions, for example if the presence of depression affects the clinical outcomes in patients treated for pain. 


  • Title: Depression and Pain Comorbidity - A Literature Review
  • Authors: Matthew J. Bair, MD, MS; Rebecca L. Robinson, MS; Wayne Katon, MD; Kurt Kroenke, MD
  • Date: November 10, 2003
  • Source: Arch Intern Med. 2003;163(20):2433-2445. doi:10.1001/archinte.163.20.2433, Jama Internal Medicine



The following link will lead you to the full text article:
Depression and Pain Comorbidity





 The Nucleus Accumbens & Resistant MDD

This review aimed to investigate the therapeutic potential of Deep Brain Stimulation for treating 
resistant Major Depressive Disorder. The researchers explored the role of Nucleus accumbens as a 
treatment target.


  • Title: The nucleus accumbens: a target for deep brain stimulation in resistant major depressive disorder
  • Authors: Cecilia Nauczyciel, Suzanne Robic, Thibaut Dondaine, Marc Verin, Gabriel Robert, Dominique Drapier, Florian Naudet and Bruno Millet
  • Date: 2013
  • Source: Journal of Molecular Psychiatry 2013, 1:17  doi:10.1186/2049-9256-1-17 © 2013 Nauczyciel et al.; licensee BioMed Central Ltd. 




The following link will lead you to the full text article:
The Nucleus Accumbens & Resistant MDD
Type D Personality and Depressive Symptoms


This study examined the relative effect of Type D personality (the tendency to experience
negative emotions and to be socially inhibited) and depressive symptoms on 5-year cardiac 
prognosis in patients with coronary artery disease.
Type D personality is more than just a marker of depression.


  • Title: Prognostic Value of Type D Personality Compared With Depressive Symptoms
  • Authors: Johan Denollet, PhD; Susanne S. Pedersen, PhD
  • Date: 2008
  • Source: Arch Intern Med. 2008;168(4):431-432. doi:10.1001/archinternmed.2007.120.




The following link will lead you to the full text article:
Type D Personality and Depressive Symptoms





 Caffeine & Depression


Caffeine is the world's most widely used central nervous system stimulant. This study that analyzes prospectively the relationship between coffee or caffeine consumption and depression risk. Does depression risk decrease with increasing caffeinated coffee consumption? Can usual caffeinated coffee consumption contribute to depression prevention?


  • Title: Coffee, Caffeine, and Risk of Depression Among Women
  • Authors: Michel Lucas, PhD, RD; Fariba Mirzaei, MD, MPH, ScD; An Pan, PhD; Olivia I. Okereke, MD, SM; Walter C. Willett, MD, DrPH; Éilis J. O’Reilly, ScD; Karestan Koenen, PhD; Alberto Ascherio, MD, DrPH
  • Date: Sep 26, 2011
  • Source: Arch Intern Med. 2011;171(17):1571-1578. doi:10.1001/archinternmed.2011.393.




The following link will lead you to the full text article:
Caffeine & Depression


Exercise & Depressive Symptoms Among CI Patients


Physical inactivity and comorbid depressive disorders are common among patients with a chronic illness and are prevalent public health problems. Does exercise training significantly reduce depressive symptoms? When are larger antidepressant effects obtained?


  • Title: Effect of Exercise Training on Depressive Symptoms Among Patients With a Chronic Illness
  • Authors: Matthew P. Herring, PhD; Timothy W. Puetz, PhD; Patrick J. O’Connor, PhD; Rodney K. Dishman, PhD
  • Date: Jan 23, 2012
  • Source: Arch Intern Med. 2012;172(2):101-111. doi:10.1001/archinternmed.2011.696.


The following link will lead you to the full text article:
Exercise & Depressive Symptoms Among CI Patients

Ascorbic Acid & Depression 

The aim of this study was to explore the effect of ascorbic acid on the action of antidepressant drugs in a clinical setting.  Ascorbic acid is a cofactor in synthesis of Noradrenalin and Serotonin.


  • Title: Effect of Ascorbic Acid on Mental Depression Drug Therapy: Clinical Study
  • Authors: Suhera M Aburawi, Fathia AGhambirlou, Asseid A Attumi, Rida A Altubuly and Ahmed A Kara
  • Date: 2014
  • Source: J Psychol Psychother 4:131. doi: 10.4172/2161-0487.1000131




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 Anxiety, Depression and Coronary Artery Disease


The results of work conducted suggested that several psychosocial risk factors contribute to the development of cardiovascular disease. These risk factors included: anger, stress, social isolation, hostility, anxiety and depression. This study examines the relationship of anxiety and depression to coronary artery disease and sudden cardiac death.


  • Title: The Influence of Anxiety and Depression on Outcomes of Patients With Coronary Artery Disease
  • Authors: James L. Januzzi Jr, MD; Theodore A. Stern, MD; Richard C. Pasternak, MD; Roman W. DeSanctis, MD
  • Date: 2000
  • Source: Arch Intern Med. 2000;160(13):1913-1921. doi:10.1001/archinte.160.13.1913.




The following link will lead you to the full text article:
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